放射肿瘤学/随机
外观
< 放射肿瘤学
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A
Acute Lymphoblastic Leukemia (ALL) Acute Myeloid Leukemia (AML) Adolescents, Cancer in Adrenocortical Carcinoma AIDS-Related Cancers Kaposi Sarcoma (Soft Tissue Sarcoma) AIDS-Related Lymphoma (Lymphoma) Primary CNS Lymphoma (Lymphoma) Anal Cancer Appendix Cancer - see Gastrointestinal Neuroendocrine Tumors Astrocytomas, Childhood (Brain Cancer) Atypical Teratoid/Rhabdoid Tumor, Childhood, Central Nervous System (Brain Cancer)
B
Basal Cell Carcinoma of the Skin - see Skin Cancer Bile Duct Cancer Bladder Cancer Bone Cancer (includes Ewing Sarcoma and Osteosarcoma and Malignant Fibrous Histiocytoma) Brain Tumors Breast Cancer Bronchial Tumors (Lung Cancer) Burkitt Lymphoma - see Non-Hodgkin Lymphoma
C
Carcinoma of Unknown Primary Central Nervous System Atypical Teratoid/Rhabdoid Tumor, Childhood (Brain Cancer) Medulloblastoma and Other CNS Embryonal Tumors, Childhood (Brain Cancer) Germ Cell Tumor, Childhood (Brain Cancer) Primary CNS Lymphoma Cervical Cancer Childhood Cancers Childhood Cardiac Tumors Treatment Cancers of Childhood, Rare Cholangiocarcinoma - see Bile Duct Cancer Chordoma, Childhood (Bone Cancer) Chronic Lymphocytic Leukemia (CLL) Chronic Myelogenous Leukemia (CML) Chronic Myeloproliferative Neoplasms Colorectal Cancer Craniopharyngioma, Childhood (Brain Cancer) Cutaneous T-Cell Lymphoma - see Lymphoma (Mycosis Fungoides and Sézary Syndrome)
D
Ductal Carcinoma In Situ (DCIS) - see Breast Cancer
E
Embryonal Tumors, Medulloblastoma and Other Central Nervous System, Childhood (Brain Cancer) Endometrial Cancer (Uterine Cancer) Ependymoma, Childhood (Brain Cancer) Esophageal Cancer Esthesioneuroblastoma (Head and Neck Cancer) Ewing Sarcoma (Bone Cancer) Extracranial Germ Cell Tumor, Childhood Extragonadal Germ Cell Tumor Eye Cancer Intraocular Melanoma Retinoblastoma
F
Fallopian Tube Cancer
G
Gallbladder Cancer Gastric (Stomach) Cancer Gastrointestinal Neuroendocrine Tumors Gastrointestinal Stromal Tumors (GIST) (Soft Tissue Sarcoma) Germ Cell Tumors Childhood Central Nervous System Germ Cell Tumors (Brain Cancer) Childhood Extracranial Germ Cell Tumors Extragonadal Germ Cell Tumors Ovarian Germ Cell Tumors Testicular Cancer Gestational Trophoblastic Disease
H
Hairy Cell Leukemia Head and Neck Cancer Heart Tumors, Childhood Hepatocellular (Liver) Cancer Histiocytosis, Langerhans Cell Hodgkin Lymphoma Hypopharyngeal Cancer (Head and Neck Cancer)
I
Intraocular Melanoma Islet Cell Tumors, Pancreatic Neuroendocrine Tumors
K
Kaposi Sarcoma (Soft Tissue Sarcoma) Kidney (Renal Cell) Cancer
L
Langerhans Cell Histiocytosis Laryngeal Cancer (Head and Neck Cancer) Leukemia Lip and Oral Cavity Cancer (Head and Neck Cancer) Liver Cancer Lung Cancer (Non-Small Cell, Small Cell, Pleuropulmonary Blastoma, Pulmonary Inflammatory Myofibroblastic Tumor, and Tracheobronchial Tumor) Lymphoma
M
Male Breast Cancer Melanoma Melanoma, Intraocular (Eye) Merkel Cell Carcinoma (Skin Cancer) Mesothelioma, Malignant Metastatic Cancer Metastatic Squamous Neck Cancer with Occult Primary (Head and Neck Cancer) Midline Tract Carcinoma With NUT Gene Changes Mouth Cancer (Head and Neck Cancer) Multiple Endocrine Neoplasia Syndromes Multiple Myeloma/Plasma Cell Neoplasms Mycosis Fungoides (Lymphoma) Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms Myelogenous Leukemia, Chronic (CML) Myeloid Leukemia, Acute (AML) Myeloproliferative Neoplasms, Chronic
N
Nasal Cavity and Paranasal Sinus Cancer (Head and Neck Cancer) Nasopharyngeal Cancer (Head and Neck Cancer) Neuroblastoma Neuroendocrine Tumors (Gastrointestinal) Non-Hodgkin Lymphoma Non-Small Cell Lung Cancer
O
Oral Cancer, Lip and Oral Cavity Cancer and Oropharyngeal Cancer (Head and Neck Cancer) Osteosarcoma and Undifferentiated Pleomorphic Sarcoma of Bone Treatment Ovarian Cancer
P
Pancreatic Cancer Pancreatic Neuroendocrine Tumors (Islet Cell Tumors) Papillomatosis (Childhood Laryngeal) Paraganglioma Paranasal Sinus and Nasal Cavity Cancer (Head and Neck Cancer) Parathyroid Cancer Penile Cancer Pharyngeal Cancer (Head and Neck Cancer) Pheochromocytoma Pituitary Tumor Plasma Cell Neoplasm/Multiple Myeloma Pleuropulmonary Blastoma (Lung Cancer) Pregnancy and Breast Cancer Primary Central Nervous System (CNS) Lymphoma Primary Peritoneal Cancer Prostate Cancer Pulmonary Inflammatory Myofibroblastic Tumor (Lung Cancer)
R
Rare Cancers of Childhood Rectal Cancer Recurrent Cancer Renal Cell (Kidney) Cancer Retinoblastoma Rhabdomyosarcoma, Childhood (Soft Tissue Sarcoma)
S
Salivary Gland Cancer (Head and Neck Cancer) Sarcoma Childhood Rhabdomyosarcoma (Soft Tissue Sarcoma) Childhood Vascular Tumors (Soft Tissue Sarcoma) Ewing Sarcoma (Bone Cancer) Kaposi Sarcoma (Soft Tissue Sarcoma) Osteosarcoma (Bone Cancer) Soft Tissue Sarcoma Uterine Sarcoma Sézary Syndrome (Lymphoma) Skin Cancer Small Cell Lung Cancer Small Intestine Cancer Soft Tissue Sarcoma Squamous Cell Carcinoma of the Skin - see Skin Cancer Squamous Neck Cancer with Occult Primary, Metastatic (Head and Neck Cancer) Stomach (Gastric) Cancer
T
T-Cell Lymphoma, Cutaneous - see Lymphoma (Mycosis Fungoides and Sèzary Syndrome) Testicular Cancer Throat Cancer (Head and Neck Cancer) Nasopharyngeal Cancer Oropharyngeal Cancer Hypopharyngeal Cancer Thymoma and Thymic Carcinoma Thyroid Cancer Tracheobronchial Tumors (Lung Cancer) Transitional Cell Cancer of the Renal Pelvis and Ureter (Kidney (Renal Cell) Cancer)
U
Unknown Primary, Carcinoma of Ureter and Renal Pelvis, Transitional Cell Cancer (Kidney (Renal Cell) Cancer Urethral Cancer Uterine Cancer, Endometrial Uterine Sarcoma
V
Vaginal Cancer Vascular Tumors (Soft Tissue Sarcoma) Vulvar Cancer
W
Wilms Tumor and Other Childhood Kidney Tumors
Y
Young Adults, Cancer in
(正在交叉链接中)
- 肛管
- 良性疾病
- 膀胱
- 脑转移
- 乳腺
- 宫颈
- 胆管癌
- 结肠
- 子宫内膜
- 癫痫
- 食管
- 胃
- 神经胶质瘤
- 头颈部
- 霍奇金淋巴瘤
- 足跟刺
- 卡波西肉瘤
- 肺癌,非小细胞肺癌
- 肺癌,小细胞肺癌
- 淋巴瘤,非霍奇金淋巴瘤
- 髓母细胞瘤
- 间皮瘤
- 黑色素瘤,皮肤
- 黑色素瘤,眼部
- 胰腺
- 前列腺
- 直肠
- 肉瘤
- 皮肤非黑色素瘤
- 脊髓压迫
- 上腔静脉综合征
- 睾丸,非精原细胞肿瘤
- 胸腺瘤
- 血管腔内放射治疗
- 肾母细胞瘤 (威姆斯瘤)
- 热疗
- 支持性护理
- RT 技术
- 质子治疗
- 肯塔基州;2009 PMID 19111269 -- "需要对创新放射治疗技术进行随机前瞻性试验。" (Halperin EC, J Am Coll Radiol. 2009 年 1 月;6(1):33-7.)
- "可以确定应在广泛临床实践中引入之前,需要在随机前瞻性临床试验中证明其效益的创新。"
- 加拿大国家癌症研究所;2008 (1975–2004) PMID 18955452 -- "三十年来肿瘤学随机对照试验的演变。" (Booth CM, J Clin Oncol. 2008 年 10 月 27 日。[提前发表])
- 回顾了 321 份评估乳腺癌、CRC 和 NSCLC 系统治疗的 RCT 报告。
- 结果:RCT 的数量和规模大幅增加。营利性赞助大幅增加(4% 至 57%,SS)。效应量保持稳定,但作者更有可能强烈支持实验组(SS)。对实验组的支持与行业赞助密切相关。
- 威斯康星州;2008 PMID 18237799 -- "健康技术评估中的随机对照试验:过度吗?还是姗姗来迟?" (Bentzen SM, Radiother Oncol. 2008 年 1 月 29 日 [提前发表])
- 牛津大学;2007 PMID 17303884 -- "何时随机试验不必要?从噪声中识别信号。" (Glasziou P, BMJ. 2007 年 2 月 17 日;334(7589):349-51.)
- RTOG;2005 (1968–2002) PMID 15728168 -- "放射肿瘤学新疗法的评价:它们比标准疗法好吗?" (Soares HP, JAMA. 2005 年 2 月 23 日;293(8):970-8.)
- 回顾了所有已完成的 III 期 RTOG 试验。57 项试验,12734 名患者
- 结果:干预组相对于标准组的生存 OR 为 1.01 (NS)。只有 10% 显著优于标准组,88% 结论不确定。
- 毒性:干预组与治疗相关的死亡率 OR 为 1.76,高于标准组 (SS)。
- 结论:无法提前预测个别试验的结果。
- COG;2005 (1955–1997) PMID 16299015 -- "儿童癌症的实验治疗是否优于既定治疗?对儿童肿瘤学组随机对照试验的观察性研究。" (Kumar A, BMJ. 2005 年 12 月 3 日;331(7528):1295. 2005 年 11 月 18 日提前发表)
- 回顾了已完成的 III 期试验。126 项试验,36567 名患者。
- 结果:生存 OR 为 0.96 (NS)。
- 结论:儿童癌症的新治疗方法与既定治疗方法相比,同样有可能效力较低,也有可能效力较高。